Unparalleled insight to answer your human liver questions.
A complete system to support your science from in vitro development to in vivo validation
A True Human Liver Model
FRG: the complete platform from in vitro development & optimization to in vivo validation.
FRG® KO IS HUMANIZED AT THE CELLULAR LEVEL
Humanized. Validated. Proven. That’s what you get from Yecuris FRG® KO technology.
- Validate specificity of targeting in gene therapy
- Understand disease pathways & processes in liver disease
- Assess human hepatotropic agents in infectious disease
- Define toxicity and metabolic attributes of compounds within the human liver
- Answer previously unapproachable questions in liver biology
Humanized Animal Models
Rigorously Refined, Globally Accessible, Market Proven for Over a Decade.
Yecuris scientists have painstakingly refined liver engraftment into FRG KO animals, yielding highly robust and stable in vitro and in vivo products that put the power of next-gen hepatic research tools in the hands of scientists worldwide.
Whether you are creating the next cure for a liver disease, testing your small molecule for metabolism or toxicology, building innovative gene therapies, or targeting NASH, you need real data with real human relevance as early as possible.
Since 2007, scientists have trusted the Yecuris FRG KO platform for their research. Yecuris FRG KO technologies include our liver-humanized mouse models, HepaCurTM cell products and CuRxTM reagents. These discovery research tools provide scientists with relevant insights into liver-specific questions at the cellular, tissue, and whole animal levels.